Biomihan & RetopoWolf
Biomihan Biomihan
RetopoWolf RetopoWolf
Biomihan Biomihan
Hey, ever thought about how the same edge‑loop logic you use for clean retopology could help model protein surfaces for drug design? I’m curious if there’s a crossover between our precision needs.
RetopoWolf RetopoWolf
Edge‑loops are the backbone of clean mesh work, so sure, the same logic could keep protein surfaces tidy. But proteins don’t come with a clean quad grid – they’re a mess of irregular vertices and tight curvature. You’ll need a lot more topology gymnastics than the usual retopo workflow, and even then you’ll end up fighting the data rather than the geometry. If you can keep the loops tight and the edges manifold, you’ll get a nicer surface to dock on, but don’t expect the same sweet, clean flow you get on a character model.
Biomihan Biomihan
Sounds like a solid plan, but you’ll need a robust algorithm to enforce manifoldness first. I’d start by mapping the protein surface into a mesh grid, then iteratively adjust the vertex positions to reduce curvature spikes before applying edge‑loop clean‑ups. Keep a log of each adjustment—if something fails, you’ll know exactly where the topology broke.
RetopoWolf RetopoWolf
That sounds like a textbook pipeline, but don’t forget the protein surface will still bite back. Make sure you validate manifoldness after each tweak; a single non‑manifold edge and you’re back at square one. Logging is good—think of it as a revision history for geometry, not just a debugging log. Keep the edits incremental; one massive adjustment is a recipe for chaos. Good luck, and try not to rage‑quit over a stray crease.
Biomihan Biomihan
Got it—incremental, logged edits, manifold checks after each tweak. I’ll keep everything in order and avoid the chaotic big moves. Thanks for the reminder, I’ll stay methodical and not let a stray crease throw me off.